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KMID : 0362919880060020247
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Journal of the Korean Society for Therapeutic Radiology and Oncology
1988 Volume.6 No. 2 p.247 ~ p.251
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Total Body Irradiation in Leukemia -Preliminary Report-
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Jang Hong-Seok
Chung Su-Mi
Choi Ihl-Bohng
Kim Choon-Yul
Bahk Yong-Whee
Kim Choon-Choo
Kim Dong-Jip
Lee Jae-Soo
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Abstract
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Total body irradiation has been applied to treat acute leukemia and chronic granulocytic leukemia. 20 patients with acute leukemia or chronic granulocytic leukemia were treated with total body irradiation using 6 MV linear accelerator before bone marrow transplantation at the Division of Therapeutic Radiology, department of Radiology, St. Mary’s Hospital, catholic University Medical College from August 1987 to September 1988.
Among 20 patients, 8 patients received 6 fractions of 200 cGy (total 1200 cGy), 10 patients received a single 850 cGy radiation, 1 patient received 4 fractions totaling 850 cGy (200, 200, 200, 250), and 1 patient received 1100 cGy in 2 fractions (850, 250). 17 patients received allogenic grafts, 2 patients received autologous grafts, and only one patients received one locus mismatched graft. 13 patients are still alive and 7 patients died. The complications induced by total body irradiation were nausea and vomiting, diarrhea, skin eruption, mucositis, and pneumonitis.
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KEYWORD
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Total body irradiation, Leukemia, Bone marrow transplantation
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